iNeu™ Human Astrocytes

Description

Astrocytes constitute 20-40% of the total number of cells in the mammalian brain and they play multifaceted and vital roles in maintaining neurophysiological function of the central nervous system (CNS) by regulating homeostasis, increasing synaptic plasticity, and sustaining neuroprotective effects. Increasingly evidence suggests astrocytes play the central role in neurodegenerative disorders, stoke and other brain injury. Human induced pluripotent stem cells (iPSCs)-derived astrocytes are a useful in vitro model for exploring its function and the molecular mechanisms of CNS diseases such as Alzheimer's disease and Parkinson's disease.

iNeu™ Human Astrocytes from Creative Biolabs are derived from human iPSCs and exhibits typical traits of physiological astrocytes, including expressing of astrocyte markers (GFAP and S100β) and cytokine-mediated inflammatory responses, which have a great potential for uncovering the mechanisms of CNS diseases.

Features

Positive for GFAP, S100β, ALDH1L1 and CD44;
Ability to co-culture with neurons or microglia;
Drug screening and neuroinflammation assay

Cell Types

Astrocytes

Species

Human

Size

1M cells/vial; 2M cells/vial

Growth Pattern

Adherent

Culture Medium

It is recommended to use iNeu™ Human Astrocytes Complete Medium(CAT#: NRYF-0824-HZ16) for culturing iNeu™ human astrocytes in vitro.

Coating Conditions

Poly-L-ornithine solution

Shipping

Dry ice

Storage

Liquid Nitrogen

Handling Advice

Upon receiving, directly and immediately transfer the cells from dry ice to liquid nitrogen and keep
the cells in liquid nitrogen until they are needed for experiments.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Quality Control

Negative for mycoplasma

Donor Health

Normal