Product
Rat Anti-MAG Monoclonal Antibody (CBP2283)
[CAT#: NAB2010216LS]
Anti-MAG Monoclonal Antibody
- Host Species:
- Rat
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; IHC-P
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Myelin-associated glycoprotein (MAG) is a cell membrane glycoprotein and a member of the siglec (sialic acid-binding immunoglobulin-like lectins) family. MAG has two isoforms in myelinated structures in the nervous system. MAG is expressed on oligodendrocytes and Schwann cells and is believed to be involved in myelination during nerve regeneration. MAG knockout mice develop quite severe pathological abnormalities associated with myelin instability.
Immunogen
Purified MAG protein isolated from human central nervous system.
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Host Species
Rat
Isotype
IgG2b, κ
Clone Number
CBP2283
Applications
WB; IHC-P
Application Notes
WB (0.5-5.0 µg/mL); IHC-P (5.0-10.0 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Handling Advice
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Dobersen MJ, et al. 1985. Neurochem Research. 4: 499
2. McKerracher L and Rosen KM. 2015. Front Mol Neurosci. 8: 51
3. Vallat JM, et al. 2016. Expert Rev Neurother. 9: 1111
2. McKerracher L and Rosen KM. 2015. Front Mol Neurosci. 8: 51
3. Vallat JM, et al. 2016. Expert Rev Neurother. 9: 1111
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
