RNAi Substrates
RNA interference (RNAi) is an intracellular gene expression regulation mechanism that can inhibit the expression of specific genes by specifically degrading mRNA. Since Andrew Fair and Craig Mello won the Nobel Prize in Physiology or Medicine in 2006 for their discovery of RNA interference, RNA interference technology has shown great potential for application in biomedical research, the development of therapeutic strategies, and the improvement of crop resistance.
Creative Biolabs offers a comprehensive range of innovative RNAi tools, siRNA products including siRNA, miRNA and lentiviral particles to support and accelerate your research in the neuroscience field.
Applications
The applications of RNA interference technology are extremely broad. It has been widely used in gene function research, disease modeling, and gene therapy.
Applications | Description |
Gene Function Research | RNAi provides a rapid and effective means of targeting and silencing specific genes to study the function of specific genes and related pathways. Using siRNA knockdown or miRNA overexpression/knockout, researchers can analyze the biological function of genes in in vitro cell culture and in vivo animal models. |
Gene Therapy | RNAi is considered to be a revolutionary therapy, especially for targeting genes and pathways that are difficult to treat with traditional drugs. Currently, a number of RNAi treatment strategies for tumors, viral infections (such as HIV and hepatitis viruses), neurodegenerative diseases, and rare diseases are now being developed or tested in preclinical trials. |
Agricultural Applications | Another potential application of RNAi is in agriculture. In crop improvement, RNAi can improve the resistance of crops to insects, salt and alkali, and drought. By silencing specific genes, the use of pesticides can be reduced, thereby improving the quality of agricultural products while protecting the environment. |
Our custom services provide ready-to-use constitutive or inducible overexpression lentiviruses for any specific gene, as well as high-titer, ready-to-use shRNA lentiviruses for your target. Please contact us to discuss your custom project or to inquire about our RNAi products.
- Applications:
- RNAi
- Applications:
- RNAi
- Applications:
- RNAi
- Applications:
- RNAi
- Applications:
- RNAi
- Applications:
- RNAi
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- NeuroMab™ Anti-F-Spondin/SPON1 Antibody, Clone N24875P (CBP11839) (Cat#: NRZP-0822-ZP4740)
- NeuroMab™ Anti-Tau Antibody(NRP-0422-P1760) (Cat#: NRP-0422-P1760)
- NeuroMab™ Anti-Amyloid Beta 1-15 Antibody(NRP-0422-P867) (Cat#: NRP-0422-P867)
- NeuroMab™ Anti-EPHB2 Antibody(NRP-0422-P1220) (Cat#: NRP-0422-P1220)
- NeuroMab™ Mouse Anti-SHANK3 Monoclonal Antibody (CBP929) (Cat#: NAB-0720-Z3477)
- NeuroMab™ Mouse Anti-LRP1 Monoclonal Antibody (CBP3363) (Cat#: NAB-0720-Z6479)
- Tau Monoclonal Antibody (AT120, HT7 and BT2 clone) (Cat#: NK-2106-P008)
- NeuroMab™ Mouse Anti-EFNB2 Monoclonal Antibody (CBP1159) (Cat#: NAB-0720-Z4396)
- NeuroMab™ Anti-Tau Antibody(NRP-0422-P1683) (Cat#: NRP-0422-P1683)
- Human Brain Vascular Adventitial Fibroblasts (Cat#: NCL-21P6-014)
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- Rat Retinal Muller Cell Line, Immortalized (Cat#: NCL-21P6-192)
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- Human Dental Pulp Stem Cells (Cat#: NRZP-1122-ZP113)
- Rat Glioma Cell Line C6 (Cat#: NCL2110P346)
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- Green Fluorescent Alpha-synuclein SH-SY5Y Cell Line (Cat#: NCL2110P209)
- Human Microglia Cell Line HMC3, Immortalized (Cat#: NCL-2108P38)
- Beta Amyloid (1-40), Aggregation Kit, TTF Assay (Cat#: NRZP-0323-ZP199)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- pAAV-syn-jGCaMP8f-WPRE (Cat#: NTA-2106-P061)
- AAV2/9-hEF1a-DIO-mCherry-P2A-TetTox-WPRE-pA (Cat#: NTA-2012-ZP268)
- AAV2/2Retro-CAG-DIO-EGFP-2A-TetTox-pA [Neural Tracing] (Cat#: NTA-2012-ZP303)
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- Dextran-CYanine5.5 (Cat#: NTA-2011-ZP118)
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- ABCA1 Antisense Oligonucleotide (NV-2106-P27) (Cat#: NV-2106-P27)
- App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged (Cat#: NEP-0421-R0053)
- Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged (Cat#: NEP-0421-R0232)
- Mouse SOD1 shRNA Silencing Adenovirus (Cat#: NV-2106-P14)
- Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0832)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP501)
- NeuroPro™ Anti-ASA BBB Shuttle Protein (Cat#: NRZP-0423-ZP504)
- NeuroPro™ Anti-idursulfase BBB Shuttle Protein (Cat#: NRZP-0423-ZP497)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP500)
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- NeuroPro™ Anti-NAGLU BBB Shuttle Protein (Cat#: NRZP-0423-ZP506)
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- NeuroPro™ Anti-EPO BBB Shuttle Protein (Cat#: NRZP-0423-ZP508)
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