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Creative Biolabs
Product

Human Cav2.1/β4/α2δ1/Kir2.1 Calcium Channel Transiently Transfected Cells

[CAT#: NCL-7P171]

Human Cav2.1/β4/α2δ1/Kir2.1 calcium ion channel-expressing, transiently transfected cells.

Species:
Human
Applications:
Calcium Assay
Cell Types:
Calcium Assay Cell; Ion Channel Cell

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Product Overview

Description

The human CACNA1A gene encodes the pore-forming subunit of Cav2.1, which is a voltage-gated P/Q calcium channel.Contains auxiliary subunits that regulate gating and pharmacological properties, while inwardly rectifying potassium channels allow the membrane potential to change with changes in extracellular K+.CACNA1A mutations are responsible for a variety of genetic neurological diseases, including familial hemiplegic migraine, type 2 paroxysmal ataxia, and spinocerebellar ataxia type 6 epilepsy.The Cav2.1 channel expressed in neurons is a therapeutic target for pain.

Cell Types

Calcium Assay Cell; Ion Channel Cell

Applications

Calcium Assay

Species

Human
Properties

Shipping

Dry ice.

Storage

Liquid Nitrogen

Research Use Only

For research use only

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
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For Research Use Only. Not For Clinical Use.
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