iNeuMab™ Anti-CXCL10 BBB Shuttle Antibody (NRZP-1022-ZP3435)

Name: iNeuMab™ Anti-CXCL10 BBB Shuttle Antibody (NRZP-1022-ZP3435)
SKU: NRZP-1022-ZP3435
Rating: 5 (1 reviews)

[CAT#: NRZP-1022-ZP3435]

Host Species:: Humanized

Species Reactivity:: Human

Applications:: WB; ELISA; IHC; Neut; Block; In Vitro; In Vivo; Antagonist

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Humanized

Isotype

IgG

Applications

WB; ELISA; IHC; Neut; Block; In Vitro; In Vivo; Antagonist

Relevant Diseases

Neuroinflammation

Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only

Target

CXCL10

Official Name

CXCL10

Full Name

chemokine (C-X-C motif) ligand 10

Alternative Names

gIP-10; INP10; 10 kDa interferon gamma-induced protein; IP-10; C-X-C motif chemokine 10; 1-73; Small-inducible cytokine B10; IFI10; Gamma-IP10; SCYB10; crg-2; C7; mob-1

Publications