iNeuMab™ Anti-CXCL10 BBB Shuttle Antibody (NRZP-1022-ZP3439)

Name: iNeuMab™ Anti-CXCL10 BBB Shuttle Antibody (NRZP-1022-ZP3439)
SKU: NRZP-1022-ZP3439
Rating: 5 (1 reviews)

[CAT#: NRZP-1022-ZP3439]

Host Species:: Human

Species Reactivity:: Human; Mouse; Cynomolgus Monkey

Applications:: WB; ELISA; IHC; Neut; In Vitro; In Vivo

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Immunogen

Mature protein human IP-10 (hIP10) (NM001565)

Species Reactivity

Human; Mouse; Cynomolgus Monkey

Clonality

Monoclonal

Host Species

Human

Isotype

IgG

Applications

WB; ELISA; IHC; Neut; In Vitro; In Vivo

Relevant Diseases

Neuroinflammation

Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only

Target

CXCL10

Official Name

CXCL10

Full Name

chemokine (C-X-C motif) ligand 10

Alternative Names

gIP-10; INP10; 10 kDa interferon gamma-induced protein; IP-10; C-X-C motif chemokine 10; 1-73; Small-inducible cytokine B10; IFI10; Gamma-IP10; SCYB10; crg-2; C7; mob-1

Publications