NeuroMab™ Anti-CXCL10 Antibody(NRP-0422-P2088)

[CAT#: NRP-0422-P2088]

A therapeutic antibody raised against Human, Mouse, Cynomolgus Monkey IP-10.

Host Species:: Human

Species Reactivity:: Human; Mouse; Cynomolgus Monkey

Applications:: WB; ELISA; IHC; Inhib; In Vitro

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Product Overview

Description

The antibody binds to IP-10 with high affinity, inhibits the binding of IP-10 to its receptor, inhibits IP-10 induced calcium flux and inhibits IP-10-induced cell migration. The antibody provides methods for treating various inflammatory and autoimmune diseases by inhibiting IP-10 activity.

Species Reactivity

Human; Mouse; Cynomolgus Monkey

Clonality

Monoclonal

Host Species

Human

Isotype

IgG

Applications

WB; ELISA; IHC; Inhib; In Vitro

Relevant Diseases

Neuroinflammation

Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

>95% by SDS PAGE or HPLC

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only

Target

CXCL10

Official Name

CXCL10

Full Name

chemokine (C-X-C motif) ligand 10

Alternative Names

gIP-10; INP10; 10 kDa interferon gamma-induced protein; IP-10; C-X-C motif chemokine 10; 1-73; Small-inducible cytokine B10; IFI10; Gamma-IP10; SCYB10; crg-2; C7; mob-1