NeuroMab™ Anti-TREM2 Antibody(NRP-0422-P827)

Product Overview

Description

The anti-TREM-2 antibody promotes TREM-2 activation and can be using as an agonist antibody therapeutically.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Applications

ELISA; In Vitro; Agonist

Relevant Diseases

Alzheimer's Disease

Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

>95% by SDS PAGE or HPLC

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only

Target

TREM2

Official Name

TREM2

Full Name

Triggering receptor expressed on myeloid cells 2

Alternative Names

TREM2; Triggering receptor expressed on myeloid cells 2

Gene ID

54209(Human)

Uniprot ID

Q9NZC2(Human)

Product Pictures

FuncS

Figure 1 is a graph showing dose-response curves of TREM-2 activation in response to treatment with anti-TREM-2 antibodies HJ23.4, HJ23.7, HJ23.8, HJ23.9, HJ23.10 and HJ23. 13. TREM-2 activation is reported as percentage of GFP relative to negative control (y-axis).

Publications