Mouse Anti-PFN2 Monoclonal Antibody (CBP2611)

[CAT#: NAB20101685CR]

Mouse Monoclonal (2H7C12) to PFN2

Host Species:: Mouse

Species Reactivity:: Human; Mouse; Rat; Porcine

Applications:: IHC; WB; ELISA

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Product Overview

Description

PFN2 (profilin 2) is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals.

Expression Host

Mammalian cells

Immunogen

PFN2 fusion protein Ag5043

Species Reactivity

Human; Mouse; Rat; Porcine

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a

Clone Number

CBP2611

Applications

IHC; WB; ELISA

Application Notes

IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Metabolism

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1500 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

PFN2

Official Name

PFN2

Full Name

Profilin 2

Alternative Names

D3S1319E; PFL; PFN2; Prifilin 2; PROF2; profilin 2; Profilin II

Gene ID

5217(Human); 18645(Mouse); 81531(Rat)

Uniprot ID

P35080(Human); Q9JJV2(Mouse); Q9EPC6(Rat)

References

1. Zhang, H., Yang, W., Yan, J., Zhou, K., Wan, B., Shi, P.,... & Li, D. (2018). Loss of profilin 2 contributes to enhanced epithelial-mesenchymal transition and metastasis of colorectal cancer. International journal of oncology, 53(3), 1118-1128. 2. Andriamoratsiresy, D., Piskunov, A., Lutzing, R., & Rochette-Egly, C. (2018). PFN2a, a new partner of RARα in the cytoplasm. Biochemical and biophysical research communications, 495(1), 846-853.

Publications