iNeuMab™ Anti-TrpV3 cation channel BBB Shuttle Antibody (NRZP-0423-ZP449)
[CAT#: NRZP-0423-ZP449]
- Species Reactivity:
- Human; Mouse; Rat
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-TRPV3 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Synthetic peptide amino acids 774-791 (cytoplasmic C-terminus) of rat TrpV3 (KTTLYAFDELDEFPETSV; NP_001020928)
Human: 77% identity (14/18 amino acids identical)
Mouse=100% identity (18/18 amino acids identical)
Common to all TrpV3 splice variants
Human: 77% identity (14/18 amino acids identical)
Mouse=100% identity (18/18 amino acids identical)
Common to all TrpV3 splice variants
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Isotype
IgG2a
Research Areas
Trp channels
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
TRPV3
Official Name
TRPV3
Full Name
TrpV3
Alternative Names
Transient Receptor Potential Cation Channel Subfamily V Member 3
Uniprot ID
NP_0010209
Publications
Publications (0)
Neural Antibodies
Neural Genes
For Research Use Only. Not For Clinical Use.
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