Cells

Cellular models are indispensable in the realm of neuroscience research, offering benefits such as cost-efficiency, easy access, adaptability, and reliable reproducibility. These models serve as in vitro tools for delving into the complexities of cellular dynamics, elucidating the underlying mechanisms, and devising potential therapeutic strategies for neurological disorders.

Creative Biolabs is passionate about offering a broad of reliable and high-quality cell products derived from different species (human, mouse, rat, monkey, rabbit, etc.). We also offer specialized cell culture media and reagents to support your neural cell-based assays in neuroscience research and drug discovery. Our devoted team is steadfast in their commitment to furnish innovative solutions that cater to the requirements of scientists and researchers in the field. Collaborate with Creative Biolabs to access state-of-the-art cell models and resources for your research endeavors.

By Cell Categories

With advanced technologies and stringent standard of quality control, we offer a range of cell products to support your research more cost-effectively. Whether for drug discovery, disease modeling or basic research, our diverse cell repository provides the flexibility and versatility needed to advance scientific knowledge and discovery.

Primary Cells Maintain the characteristics and functions of the origin of the tissues.	Immortalized Cell Lines Proliferate indefinitely with features close to primary cells.	iPSC and iPSC-derived Cells Powerful cell models from normal and disease donors.
Cell Lines More easily transfected compared to primary neural cells and proliferate.	Cell Lysates Ready to use, convenient and cost effective.

By Cell Types

We are proud to offer dozens of cell types, including but not limited to central and peripheral nerve cells. Each cell type is meticulously characterized and quality-tested to ensure reliability and consistency in research and experimentation.

Astrocytes	Neurons	Microglia	Neural Stem Cells
Neural Progenitor Cells	Oligodendrocytes (OPC)	Schwann Cells	BBB-related Cells
Meningeal Cells	Visual System-related Cells	Tooth-related Cells	Olfactory System-related Cells
Tumor Cells	Other Glial Cells	Other Cells

By Neurological Disease Models

We offer a range of verified cell models specifically used for neurological disease research. Our in vitro models encompass a wide range of neurological conditions to support diverse research needs.

AD-related Cells
PD-related Cells
HD-related Cells
ALS-related Cells
Epilepsy-related Cells		Brain Tumor-related Cells

We also provide custom primary cell isolation services, cell immortalization services, cell line development service and cell-based assay to meet your specific scientific needs by integrating cutting-edge technologies and adhering to strict standards of quality control. Please feel free to contact us to speed up your research progress.

References

1. Wasielewska, Joanna M et al. "Modeling the Blood–Brain Barrier to Understand Drug Delivery in Alzheimer's Disease." Alzheimer's Disease: Drug Discovery. 2020, Dec 18. Chapter 7
2. Barak, M et al. "Human iPSC-Derived Neural Models for Studying Alzheimer's Disease: from Neural Stem Cells to Cerebral Organoids." Stem Cell Rev and Rep. 2022, 18(2):792-820.
3. Cabral-Costa, João Victor, and Alicia J Kowaltowski. "Mitochondrial Ca2+ handling as a cell signaling hub: lessons from astrocyte function." Essays Biochem. 2023, 67(1):63-75.
4. Zhang, Yi et al. "Maternal sevoflurane exposure affects differentiation of hippocampal neural stem cells by regulating miR-410-3p and ATN1." Stem Cell Res Ther. 2020, 11(1):423.
5. Yip, Jackson L K et al. "AGS3 and Gαi3 Are Concomitantly Upregulated as Part of the Spindle Orientation Complex during Differentiation of Human Neural Progenitor Cells." Molecules. 2020, 25(21):5169.
6. Plastini, Melanie J et al. "Transcriptional abnormalities in induced pluripotent stem cell-derived oligodendrocytes of individuals with primary progressive multiple sclerosis." Front Cell Neurosci. 2022, 16:972144.
7. Milichko, Valentin, and Vyacheslav Dyachuk. "Novel Glial Cell Functions: Extensive Potency, Stem Cell-Like Properties, and Participation in Regeneration and Transdifferentiation." Front Cell Dev Biol. 2020, 8:809.
8. Alcendor, Donald J. "Human Vascular Pericytes and Cytomegalovirus Pathobiology." Int J Mol Sci. 2019, 20(6):1456.
9. Su, Yun et al. "Meningeal immunity and neurological diseases: new approaches, new insights." J Neuroinflammation. 2023, 20(1):125.
10. Kanamaru, Manami et al. "Simulation-Based Clarification of Appropriate Factors for Presenting Phosphene in Two Directions Avoiding Electrical Interference." Bioengineering (Basel). 2021, 8(8):111.
11. Rodas-Junco, Beatriz A et al. "Stem Cells from Dental Pulp: What Epigenetics Can Do with Your Tooth." Front Physiol. 2017, 8:999.
12. Kim, Chuntae et al. "Artificial olfactory sensor technology that mimics the olfactory mechanism: a comprehensive review." Biomater Res. 2022, 26(1):40.
13. Shi, Zhen-Duo et al. "Tumor cell plasticity in targeted therapy-induced resistance: mechanisms and new strategies." Signal Transduct Target Ther. 2023, 8(1):113.
14. Andreeva, Daria et al. "Satellite Glial Cells: Morphology, functional heterogeneity, and role in pain." Front Cell Neurosci. 2022, 16:1019449.
15. Amartumur, S et al. "Neuropathogenesis-on-chips for neurodegenerative diseases." Nature Communications. 2024, 15(2219).
16. Parsons, Anna L M et al. "The Interconnected Mechanisms of Oxidative Stress and Neuroinflammation in Epilepsy." Antioxidants (Basel). 2022, 11(1):157.
17. Antonica, Francesco et al. "Modeling Brain Tumors: A Perspective Overview of in vivo and Organoid Models." Front Mol Neurosci. 2022, 15:818696.

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iNeu™ Microglia TREM2 R47H, Donor 10, AHN [CAT#: NCL-7P050]

Female, TREM2 R47H, Apparently Healthy Normal (AHN)

Species:

Human

Cell Types:

Microglia

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iNeu™ Microglia TREM2 R47H Kit, Donor 10, AHN [CAT#: NCL-7P045]

Female, TREM2 R47H, Apparently Healthy Normal (AHN)

Species:

Human

Cell Types:

Microglia

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iNeu™ Microglia AD TREM2 HZ, Disease Model [CAT#: NCL-7P015]

Microglia Alzheimer's Disease differentiated from Human iPS cells, frozen

Species:

Human

Cell Types:

Microglia

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Datasheet MSDS

iNeu™ Microglia AD TREM2 HO, Disease Model [CAT#: NCL-7P014]

Microglia Alzheimer's Disease differentiated from Human iPS cells, frozen

Species:

Human

Cell Types:

Microglia

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Datasheet MSDS

iNeu™ Microglia AD TREM2 HZ Kit, Disease Model [CAT#: NCL-7P013]

Microglia Alzheimer's Disease differentiated from Human iPS cells, frozen

Species:

Human

Cell Types:

Microglia

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Datasheet MSDS

iNeu™ Microglia AD TREM2 HO Kit, Disease Model [CAT#: NCL-7P012]

Microglia Alzheimer's Disease differentiated from Human iPS cells, frozen

Species:

Human

Cell Types:

Microglia

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Datasheet MSDS