NeuroMab™ Anti-CD14 BBB Shuttle Antibody,Clone NR2489P
[CAT#: NRZP-1022-ZP3706]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA; FC
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Clone Number
NR2489P
Applications
ELISA; FC
Relevant Diseases
Neuroinflammation
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
CD14
Official Name
CD14
Full Name
Cluster of differentiation 14
Alternative Names
IVL
Product Pictures
ELISA
Figure 1 shows the results of an ELISA in which CD14-Fc, ICAM3-Fc and IgG were coated on a plate and screened phage antibodies were allowed to bind to CD14-Fc, ICAM3-Fc or IgG.
Inhib
Figure 2A shows the ability of Ce3 to inhibit the interaction of AC with macrophages and thus block the clearance of AC.
Inhib
Figure 2B shows the ability of Ce3 to inhibit the interaction of AC with macrophages and thus block the clearance of AC.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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