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Creative Biolabs

Mouse Anti-CD14 Monoclonal Antibody (CBP2524)

[CAT#: NAB2007FY860]

Mouse Monoclonal [biG53] to CD14

Host Species:
Mouse
Species Reactivity:
Mouse
Applications:
FC

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Product Overview

Description

Mouse anti-mouse CD14 antibody recognizes mouse CD14, which is a 55kD sugar-phosphoinositide-linked cell surface protein that also exists in soluble form. The expression of CD14 is restricted to the myeloid lineage, and is mainly expressed on peripheral blood mononuclear cells, weakly expressed on granulocytes, but not expressed on myeloid progenitor cells. The CD14 molecule acts as a pattern recognition receptor and can bind lipopolysaccharide (LPS) and other microbial products such as lipoprotein acids, lipoproteins and peptidoglycans. The binding of LPS to CD14 mediates the innate immune response to LPS, and the Toll-like receptor 4 (TLR4)/MD-2 complex is required to effectively send out signals.

Immunogen

Recombinant mouse CD14.

Species Reactivity

Mouse

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2524

Applications

FC

Relevant Diseases

Alzheimer's Disease; Neurodegenerative Disease

Research Areas

Neuroregeneration

Conjugation

RPE
Product Properties

Form

Lyophilized

Formulation

PBS, 0.09% Sodium Azide, 1% BSA, 5% Sucrose

Preservatives

YES

Purification

Protein G

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at +4°C. DO NOT FREEZE. This product should be stored undiluted. Should this product contain a precipitate we recommend micr°Centrifugation before use.

Handling Advice

Reconstitute with 1ml distilled water

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CD14

Official Name

CD14

Full Name

CD14 Molecule

Alternative Names

CD14 Molecule; CD14 Antigen; Myeloid Cell-Specific Leucine-Rich Glycoprotein

Gene ID

929(Human); 12475(Mouse); 60350(Rat)

Uniprot ID

P08571(Human); P10810(Mouse); Q63691(Rat)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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