Mouse Anti-CD14 Monoclonal Antibody (CBP2524)
[CAT#: NAB2007FY860]
Mouse Monoclonal [biG53] to CD14
- Host Species:
- Mouse
- Species Reactivity:
- Mouse
- Applications:
- FC
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
Mouse anti-mouse CD14 antibody recognizes mouse CD14, which is a 55kD sugar-phosphoinositide-linked cell surface protein that also exists in soluble form. The expression of CD14 is restricted to the myeloid lineage, and is mainly expressed on peripheral blood mononuclear cells, weakly expressed on granulocytes, but not expressed on myeloid progenitor cells. The CD14 molecule acts as a pattern recognition receptor and can bind lipopolysaccharide (LPS) and other microbial products such as lipoprotein acids, lipoproteins and peptidoglycans. The binding of LPS to CD14 mediates the innate immune response to LPS, and the Toll-like receptor 4 (TLR4)/MD-2 complex is required to effectively send out signals.
Immunogen
Recombinant mouse CD14.
Species Reactivity
Mouse
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP2524
Applications
FC
Relevant Diseases
Alzheimer's Disease; Neurodegenerative Disease
Research Areas
Neuroregeneration
Conjugation
RPE
Product Properties
Form
Lyophilized
Formulation
PBS, 0.09% Sodium Azide, 1% BSA, 5% Sucrose
Preservatives
YES
Purification
Protein G
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at +4°C. DO NOT FREEZE. This product should be stored undiluted. Should this product contain a precipitate we recommend micr°Centrifugation before use.
Handling Advice
Reconstitute with 1ml distilled water
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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