NeuroMab™ Anti-SLC38A1 Monoclonal Antibody (CBP2355)

Product Overview

Description

SNAT1, also called sodium-coupled neutral amino acid transporter 1, plays an essential role in glutamine uptake and neurotransmitter recycling. SNAT1 has been shown to mediate the co-transport of glutamine and sodium ions in a pH-sensitive manner, and contributes to the replenishment of neurotransmitters glutamate and GABA.

Species Reactivity

Mouse

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP2355

Applications

Application Notes

WB (2-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1739

Product Properties

Form

Liquid

Formulation

This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.

Handling Advice

Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

SLC38A1

Official Name

SLC38A1

Full Name

Sodium-coupled neutral amino acid transporter 1

Alternative Names

SLC38A1; ATA1; NAT2; SAT1; SNAT1; solute carrier family 38 member 1

Gene ID

81539 (Human); 105727 (Mouse)

Uniprot ID

Q9H2H9 (Human); Q8K2P7 (Mouse)

References

1. Schioth HB, et al. 2013. Mol Aspects Med. 34(2-3):571
2. Mackenzie B, et al. 2004. Pflugers Arch. 447(5):784
3. Conti F, et al. 2006. Neurochem Int. 48(6-7):459

Publications