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Creative Biolabs

NeuroMab™ Mouse Anti-Orexin Receptor 2 Monoclonal Antibody (CBP2388)

[CAT#: NAB2010410LS]

Anti-Orexin Receptor 2 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human; Baboon
Applications:
FC; ICC; IF

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Product Overview

Description

CD200R, also known as OX2R, is a membrane glycoprotein with up to 70% of its weight derived from N-linked glycosylation. CD200R is expressed primarily by monocytes and neutrophils, but also by other leukocytes including T cells and mast cells. The interaction between CD200 and CD200R may contribute to pathways that suppress and limit macrophage induced inflammatory damage in tissues.

Species Reactivity

Human; Baboon

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP2388

Applications

FC; ICC; IF

Application Notes

FCM (≤ 2 µg per 106 cells in 100 µl volume or 100 µl of whole blood)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1757
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

Orexin Receptor 2

Official Name

HCRTR2

Full Name

Orexin receptor type 2

Alternative Names

HCRTR2; OX2R; Hypocretin (orexin) receptor 2; hypocretin receptor 2

Gene ID

3062(Human); 387285(Mouse); 25605(Rat)

Uniprot ID

O43614(Human); P58308(Mouse); P56719(Rat)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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