iNeu™ Microglia Rett Syndrome MECP2, Disease Model
Microglia Rett Syndrome differentiated from Human iPS cells, frozen
- Species:
- Human
- Cell Types:
- Microglia
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Description
Microglial dysfunction is considered a key factor in neurodegenerative diseases, including Alzheimer's disease (AD). The limited availability and inconsistency of primary Human microglia limit research and treatment progress.
Rett syndrome (RTT) is a devastating neurodevelopmental disorder, mainly caused by mutations in the MECP2 gene. MECP2 encodes a 486 amino acid protein that binds to methylated DNA and usually down-regulates transcription.
Features
Reproducible research: Rigorous quality control and large-scale manufacturing capabilities ensure consistent performance from every lot of iNeu Microglia (>80% TREM2+, IBA1+, CX3CR1+).
Rapid results: iNeu Microglia are fully differentiated cells (not precursors) allowing for more experiments in less time.
Disease lines available: TREM2, SNCA and MeCP2 engineered mutants and isogenic control.
Cell Types
Species
Size
Tissue Source
Age
Mycoplasma Testing
Shipping
Storage
Research Use Only
Quality Control
Target
Gender
Donor Age
Donor Health
Ethnicity
Additional Donor Information
Publications (0)