Ion Channel Receptor Related Research Reagents
Ion channel receptors are multimeric proteins located on the plasma membrane. Each of these proteins can arrange themselves, forming channels or pores that extend from one side of the membrane to the other, allowing ions to pass through the channel pores. Ion channels control membrane current by opening and closing their channels to establish membrane potential. In the ion channel, ions are transported along the concentration gradient, while the ion pump / carrier is actively transporting ions against the ion gradient. Their functions include establishing quiescent membrane potentials, shaping action potentials and other electrical signals by controlling ion flow across cell membranes, controlling ion flow across secretory and epithelial cells, and regulating cell volume.
Ion channels can be classified according to their different gating methods or the type of ions passing through the channel.
Classification by gating：
Ion channels can be classified by gating, that is, different stimuli that open and close channels. It can be divided into:
Voltage-gated ion channels: the opening or closing depends on the voltage gradient on the plasma membrane. It includes voltage-gated sodium channels, voltage-gated calcium channels, voltage-gated potassium channels, cyclic nucleotide-gated channels, and voltage-gated proton channels.
Ligand-gated ion channels: the opening or closing depends on the binding of the ligand to the channel.
G protein-gated ion channel: a family of transmembrane ion channels in neurons and atrial muscle cells, which are directly controlled by G protein.
Classification by ion type：
- Chloride channel
- Potassium channel
- Sodium channels (NaVs)
- Calcium channels (CaVs)
- Proton channel
- Non-selective cation channel
- Transient receptor potential (TRP) channel
Creative Biolabs has been committed to developing the most advanced reagents to assist neurobiological research. We provide a series of scientific research products for Ion channel receptors research, including monoclonal antibodies, polyclonal antibodies, labeled antibodies, proteins, analytical kits, and small molecule activators and inhibitors.
Please browse the options below to take a deeper look at the tools for your research needs.
Target
Calcium Channel Related Research Reagents
Potassium Channel Related Research Reagents
Sodium Channel Related Research Reagents
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HPCAL4 Mouse Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC
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- iNeu™ Human Oligodendrocyte Progenitor Cells (OPCs) (Cat#: NCL-2103-P49)
- Human Retinal Epithelial Cell ARPE-19 (Cat#: NCL2110P069)
- Human Glial (Oligodendrocytic) Hybrid Cell Line (MO3.13) (Cat#: NCL-2108P34)
- Rat Muller Cell (Cat#: NCL2110P040)
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- Mouse Retinal Ganglion Cells (Cat#: NCL2110P145)
- Mouse Glioma Cell Line GL-261-Luc (Cat#: NCL-2108P06)
- iNeu™ Human Sensory Neurons (Cat#: NCL-2103-P62)
- Mouse Microglia Cell Line BV-2, Immortalized (Cat#: NCL2110P153)
- Mouse Microglia N9 (Cat#: NCL2110P073)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
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- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
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- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
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- VSV-eGFP (Cat#: NTA-2011-ZP20)
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