Mouse Anti-Rabbit ITGAM Monoclonal Antibody (CBP1597)

Product Overview

Description

The mouse anti-Rabbit CD11b antibody recognizes rabbit CD11b cell surface glycoproteins, also known as integrin αM chain and MAC-1. Mouse anti-Rabbit CD11b antibody can immunoprecipitate two proteins with molecular weights of 165 kD and 95 kD from granulocytes. It recognizes monocytes, macrophages and neutrophils by flow cytometry and is considered to have the opposite homology to human CD11b. In immunohistochemistry, good staining of macrophages was observed.

Immunogen

Rabbit adherent blood leucocytes.

Species Reactivity

Rabbit

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP1597

Applications

FC; IF; IHC-Fr; IP

Application Notes

FCM (1/100-1/200)

Relevant Diseases

Alzheimer's Disease

Research Areas

Growth and Development

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS
0.09% Sodium Azide

Concentration

1 mg/ml

Purification

Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at +4°C or at -20°C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend micr°Centrifugation before use.

Target

CD11b

Official Name

ITGAM

Full Name

Integrin alpha M

Alternative Names

ITGAM; CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6; integrin subunit alpha M

Gene ID

3684 (Human); 16409 (Mouse); 25021 (Rat)

Uniprot ID

P11215 (Human); P05555 (Mouse)

References

1. Hoefer, I.E. et al. (2005) Aspirin, but not clopidogrel, reduces collateral conductance in a rabbit model of femoral artery occlusion.
2. Vinukonda, G. et al. (2010) Neuroprotection in a rabbit model of intraventricular haemorrhage by cyclooxygenase-2, prostanoid receptor-1 or tumour necrosis factor-alpha inhibition.
3. Xu, Y. et al. (2010) Adenovirus-mediated overexpression of glutathione-s-transferase mitigates transplant arteriosclerosis in rabbit carotid allografts.
4. Dewals, B. et al. (2008) Malignant catarrhal fever induced by alcelaphine herpesvirus 1 is associated with proliferation of CD8+ T cells supporting a latent infection.

Publications