Hydrocephalus Related Research Tools

Hydrocephalus (HC) is a condition where abnormal cerebrospinal fluid (CSF) is build up in the cavities of the brain. It is also called water in the brain. HC can be present at birth or developed in childhood or adulthood. It is divided into different categories, acquired hydrocephalus, congenital hydrocephalus, communicating hydrocephalus, non-communication hydrocephalus, normal pressure hydrocephalus and hydrocephalus ex-vacuo.

Now, little is understood about the causes of hydrocephalus. It is classically defined as a result of a dynamic imbalance between the production and absorption of CSF. The fluid accumulates in the two large lateral ventricles, resulting in an enlarged brain and skull. The accumulation of fluid eventually may cause neurological symptoms such as convulsions, intellectual disability, and epileptic seizures.

Creative Biolabs offers a wide range of tools, including specific antibodies as well as peptides and proteins targeting different biological processes of hydrocephalus. Our products are keenly sought by neuroscience researchers, particularly those applicable to studies involving hydrocephalus cause and various pathways.

Pathways Related to Hydrocephalus

Super pathways	Genes
PI3K-Akt signaling pathway	PTEN, PIK3R2, FGFR3, FGFR2, CCND2, AKT3
NFAT and cardiac hypertrophy	PTEN, PIK3R2, FGFR3, FGFR2, AKT3
Pathways in cancer	PTEN, PIK3R2, FGFR3, FGFR2, CCND2, AKT3
ErbB signaling pathway	PTEN, PIK3R2, FGFR3, FGFR2, AKT3
Apoptosis pathway	PIK3R2, FGFR3, FGFR2, AKT3

Molecular Functions Related to Hydrocephalus

Functions	Genes
Protein binding	ZIC3, WDR81, STK36, PTEN, PLOD1, PIK3R2
Protein kinase activity	STK36, FGFR3, FGFR2, CCND2, AKT3
Fibroblast growth factor-activated receptor activity	FGFR3, FGFR2

For Research Use Only. Not For Clinical Use.

Target

GBA

RGMA

Amyloid Beta

SLC27A4

CacyBP

Tau

LRRK2

PAK1

SPOCK1

Neurofilament H

NKX2.2

EURL

AGRP

Presenilin 2

S100 Beta

Synapsin I

PACSIN1

FABP3

PVRL1/NECTIN1

PGP9.5

CRMP2

PAK3

LNX

CD45

Sarcoplasmic Reticulum

GLP1

Huntingtin

GRIP1

Gemin 3

Axin 2

PHOX2A

Nucleoside Phosphorylase