Bell's Palsy Related Research Tools

Bell's palsy is a disorder caused by damage to the facial nerve that supports the muscles of the face. It is also called facial palsy. Bell’s palsy is marked by a droopy appearance on one side of the face and the inability to open or close the eye on the other affected side. Other common symptoms include drooping of one corner of the mouth, difficulty eating and drinking, facial weakness, flattening of the creases and folds in the skin, a sagging lower eyelid, headache and sensitivity to sound.

Bell's palsy occurs due to a malfunction of the facial nerve, cranial nerve VII. Inflammation of the facial nerve may lead to pressure on the nerve, blocking the transmission of neural signals or damaging the nerve. Although the cause of Bell's palsy is unknown, some research shows that the viruses and bacteria may be related to the development of Bell’s palsy (e.g. herpes simplex, HIV, sarcoidosis, herpes zoster virus, Epstein-Barr virus, or Lyme disease, a bacterial infection caused by infected ticks).

Fig.1 Anatomy of the facial nerve: topographic diagnosis.

Creative Biolabs aims to provide biological reagents to help understand the cause and pathophysiology of Bell's palsy. These reagents include but are not limited to monoclonal antibodies, polyclonal antibodies, labeled antibodies, proteins, analytical kits, and small molecule activators and inhibitors.

Biological Processes and Genes Related to Bell's Palsy

Biological Processes	Genes
NOD-like receptor signaling pathway	IFNA1, DEFA3, DEFA1, ANTXR2
Defense response to gram-negative bacterium	DEFA3, DEFA1, CD4
Intracellular estrogen receptor signaling pathway	DEFA3, DEFA1
Mitochondrial fission	PRKN, MX1
Positive regulation of T cell proliferation	IL2RA, CD40LG, CD4
Membrane disruption in other organisms	DEFA3, DEFA1
Defense response to virus	MX1, IFNA1, DEFA3, DEFA1
Defense response	MX1, IFNA1, DEFA3, DEFA1

For Research Use Only. Not For Clinical Use.

Target

Fatty Acid Synthase

NF2

Alpha Internexin

Engrailed 1

Huntingtin

KRIT1

p39

GSTP1

NT-4

Calretinin

QPRT

VRK1

WNT6

MSR1

ECEL1

Choline Acetyltransferase

Mint-1

Neuroligin 1

Alpha Synuclein

Vaspin

GFAP

FTO

Syntaxin

GLP1

NEFM

Ataxin 1

Tau

ACTA1

FABP4

PGP9.5

galectin 9/Gal-9

NME2

Related Products

Target: Calretinin

NeuroMab™ Mouse Anti-CALB2 Monoclonal Antibody (CBP2788) [CAT#: NAB20101865CR]

Mouse Monoclonal (2D7A9) to CALB2

Host Species:: Mouse

Species Reactivity:: Human; Mouse; Porcine; Rat

Applications:: IHC; WB; ELISA

Conjugation:: Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1894

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Bell's Palsy Related Research Tools

Biological Processes and Genes Related to Bell's Palsy

Target

The Spectrum of Stem Cell-Based Neuronal Models and Their Fit for Purpose