Product
Mouse Anti-SERPINI1 Monoclonal Antibody (CBP2884)
[CAT#: NAB20101962CR]
Mouse Monoclonal (1G4C6) to SERPINI1
- Host Species:
- Mouse
- Species Reactivity:
- Human; Porcine
- Applications:
- WB; ELISA
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Neuroserpin is a member of the serpin family of serine protease inhibitors predominantly expressed in the nervous system, such as s the cerebral cortex, hippocampus and the spinal cord.Neuroserpin exerts protective effects in neurons against excitotoxicity both in vitro and in vivo. Its proteolytic inhibitory activity is shown to protect neurons against damage caused by plasmin activation. Mice overexpressing neuroserpin exhibited loss of tPA activity in the brain. Overexpression of neuroserpin in primary neurons leads to increased dendritic arborization and altered dendritic spine shape.
Expression Host
Mammalian cells
Immunogen
Neuroserpin fusion protein Ag28636
Species Reactivity
Human; Porcine
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP2884
Applications
WB; ELISA
Application Notes
WB : 1:500-1:1000
Research Areas
Growth and Development
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, 0.1% sodium azide and 50% glycerol pH 7.3.
Preservatives
Yes
Concentration
1000 μg/ml
Purification
Antigen affinity purification
Purity
>95%, as determined by SDS-PAGE
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at -20°C. Stable for one year after shipment.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
Neuroserpin
Official Name
SERPINI1
Full Name
Serpin peptidase inhibitor, clade I (neuroserpin), member 1
Alternative Names
DKFZp781N13156; neuroserpin; Peptidase inhibitor 12; PI 12; PI12; Serpin I1; SERPINI1
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
