Acute Spinal Cord Injury Related Research Tools

Acute spinal cord injury (SCI) is a traumatic injury that either results in a bruise, a partial tear, or a complete tear in the spinal cord. It is a common cause of permanent disability and death in children and adults. The most common symptoms of acute spinal cord injuries may include:

Muscle weakness
Loss of voluntary muscle movement in the chest, arms, or legs
Breathing problems
Loss of feeling in the chest, arms, or legs
Loss of bowel and bladder function

Efforts to prevent SCI include individual measures (e.g. safety equipment), societal measures (e.g. safety regulations in sports and traffic) and improvements of equipment. Improved emergency care, aggressive treatment and rehabilitation can minimize damage to the nervous system and even restore limited abilities. However, spinal cord injuries require long-term physical and occupational therapy if it interferes with activities of daily life.

Creative Biolabs aims to help our customers understand and diagnose acute spinal cord injury. We provide up-to-date products that are needed in SCI study. They include but are not limited to cell lines, monoclonal antibodies, polyclonal antibodies, labeled antibodies, proteins, analytical kits, and small molecules.

Pathways and Targets Related to Creative Biolabs SCI Products

Pathways	Affiliating Targets
PEDF Induced Signaling	TNF, NOS2, NGFR, LEP, IL6, GRIN1
Cytokine Signaling in the Immune System	TNF, NOS2, MMP9, IL6, GRIN1, GDNF
Toll-like Receptor Signaling Pathway	TNF, NOS2, MMP9, IL6, CXCL8, CASP3
Pathways in Cancer	NOS2, MMP9, IL6, CXCL8, CASP3
IL-17 Family Signaling Pathway	TNF, MMP9, IL6, CXCL8, CASP3
Toll Comparative Pathway	TNF, NOS2, IL6, CXCL8
Circadian Rythm Related Genes	NOS2, NGFR, LEP, IL6
Pathogenic Escherichia coli Infection	TNF, IL6, CXCL8, CASP3
Transcriptional Misregulation in Cancer	NGFR, MMP9, IL6, CXCL8
Allograft Rejection	TNF, IL6, GDNF, CXCL8, CASP3

For Research Use Only. Not For Clinical Use.

Target

Gemin 2

CD29

S100 Beta

IL-6

Nitro tyrosine

PGP9.5

Amyloid Beta

GFAP

NOS1AP

Gephyrin

Synaptogyrin 3

Beta Arrestin 1

PPAR Gamma

STAT3 Phospho (Ser727)

Neuroligin 3

SLCO2B1

NF2

Fatty Acid Synthase

Ndufs1

ITM2B

Drebrin

CUTA

Neurogranin

Neurofilament L

IRS1

Entactin/NID

NCS1

CT A

BIN1

PARK7

PER2

APLP2