Product Overview

Immunogen

Human PDGFRβ Recombinant Protein

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b, κ

Clone Number

CBP2264

Applications

Block

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

0.2 µm filtered in PBS, pH 7.2, containing no preservative.

Concentration

Batch Dependent

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Endotoxin Level

<0.01 EU/µg of the protein

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

PDGFRB

Official Name

PDGFRB

Full Name

Platelet-derived growth factor receptor beta

Alternative Names

PDGFRB; CD140B; IBGC4; IMF1; JTK12; PDGFR; PDGFR-1; PDGFR1; KOGS; PENTT; platelet derived growth factor receptor beta

Gene ID

5159 (Human); 18596 (Mouse)

Uniprot ID

P09619 (Human); P05622 (Mouse)

References

1. Tiesman J and Hart CE. 1993. J. Biol. Chem. 13:9621-8.
2. Lindahl P, et al. 1997. Science 277:242.
3. Hart CE, et al. 1998. Science. 240:1529.
4. Borkham-Kamphorst E, et al. 2004 Lab Invest. 84:766.
5. Lennartsson J, et al. 2006. J. Biol. Chem. 281:39152.
6. Van den Akker NM, et al. 2008 Dev. Dyn. 237: 494.
7. Toffalini F, Demoulin JB. 2010. Blood 116:2429.
8. Shan H, et al. 2011. Cancer Sci. 102:1904.
9. Demoulin JB, Montano-Almendras CP. 2012. Am. J. Blood Res. 2:44.
10. Heldin CH, Lennartsson J. 2013. Cold Spring Harb. Perspect. Biol. 5:a009100.
11. Weissmueller S, et al. 2014 Cell. 157:382.
12. Fantauzzo KA, Soriano P. 2016. Genes Dev. 30:2443.

Publications