BDNF shRNA Plasmid Expression Vector Set

Name: BDNF shRNA Plasmid Expression Vector Set
SKU: NRYF-0925-XY361
Rating: 5 (1 reviews)

[CAT#: NRYF-0925-XY361]

Target:: BDNF

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Product Overview

Description

A comprehensive tool for the targeted knockdown of Brain-Derived Neurotrophic Factor (BDNF), a crucial neurotrophin for neuronal survival and plasticity. The set includes three validated shRNA plasmid vectors targeting different BDNF sequences, plus a non-targeting scrambled shRNA plasmid as a negative control. It is essential for investigating the role of BDNF in learning, memory, and neuropsychiatric disorders.

Properties

Size

5-50 μg

Shipping

Ambient

Storage

4°C

Research Use Only

Target Details

Target

BDNF

Full Name

Tissue-Type Plasminogen Activator

Gene ID

5327

Uniprot ID

P00750

Target Overview

Tissue-type plasminogen activator (tPA) is a serine protease that is a fundamental component of the fibrinolytic system, the body's mechanism for breaking down blood clots. The primary function of tPA is to convert the inactive zymogen, plasminogen, into its active form, plasmin. Plasmin is the enzyme that directly degrades the fibrin mesh that forms the structural foundation of a clot. Due to its potent clot-dissolving (thrombolytic) properties, recombinant tPA is used as a critical emergency medication for treating patients with ischemic stroke, myocardial infarction (heart attack), and pulmonary embolism.

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