Mouse Anti-TBP Monoclonal Antibody (CBP2704)
[CAT#: NAB20101780CR]
Mouse Monoclonal (2H3B2) to TBP
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat; Porcine
- Applications:
- FC; IF; IHC; IP; WB; ELISA
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
Product Overview
Description
The TATA binding protein (TBP) is a transcription factor that binds specifically to a DNA sequence TATA box. This DNA sequence is found about 25-30 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP, along with a variety of TBP-associated factors, make up the TFIID, a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20% of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II. This antibody recognize human TBP with MW 40 kDa and mouse/rat Tbp with MW 34 kDa.
Expression Host
Mammalian cells
Immunogen
TBP fusion protein Ag12383
Species Reactivity
Human; Mouse; Rat; Porcine
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2a
Clone Number
CBP2704
Applications
FC; IF; IHC; IP; WB; ELISA
Application Notes
IF : 1:20-1:200; IHC : 1:20-1:200; IP : 0.5-4.0 ug; WB : 1:500-1:1000
Research Areas
Neurogenesis
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, 0.1% sodium azide and 50% glycerol pH 7.3.
Preservatives
Yes
Concentration
1500 μg/ml
Purification
Antigen affinity purification
Purity
>95%, as determined by SDS-PAGE
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at -20°C. Stable for one year after shipment.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Zhang, M., Deng, X., Guan, X., Geng, L., Fu, M., Zhang, B.,... & Li, M. (2018). Herpes simplex virus type 2 infection-induced expression of CXCR3 ligands promotes CD4+ T cell migration and is regulated by the viral immediate-early protein ICP4. Frontiers in immunology, 9, 2932. 2. Lyu, C., Zhang, Y., Gu, M., Huang, Y., Liu, G., Wang, C.,... & Gu, Y. (2018). IRAK-M Deficiency exacerbates ischemic neurovascular injuries in experimental stroke mice. Frontiers in cellular neuroscience, 12, 504. 3. Fukumoto, J., Sidramagowda Patil, S., Krishnamurthy, S., Saji, S., John, I., Narala, V. R.,... & Soundararajan, R. (2019). Altered expression of p63 isoforms and expansion of p63-and club cell secretory protein-positive epithelial cells in the lung as novel features of aging. American Journal of Physiology-Cell Physiology, 316(4), C492-C508.
Neural Antibodies
Biomaterials
For Research Use Only. Not For Clinical Use.
