Anti-Doc2b Monoclonal Antibody (CBP4008)

[CAT#: NAB20121017LS]

Anti-Doc2b Monoclonal Antibody

Host Species:: Mouse

Species Reactivity:: Human; Rat

Applications:: WB

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Product Overview

Description

Double C2-like domain-containing protein beta (DOC2b) is a SNARE-related protein that binds to syntaxin-4 in a calcium-dependent manner to regulate exocytosis. DOC2b is stimulated by insulin to mediate glucose intake in the pancreas and can modulate release of neurotransmitters in the CNS.

Immunogen

This monoclonal antibody was raised against a fusion protein corresponding to amino acids 1-216 (N-terminus) of rat Doc2b.

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP4008

Applications

Application Notes

WB (1.0-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

DOC2B

Official Name

DOC2B

Full Name

Double C2 Domain Beta

Alternative Names

Double C2 Domain Beta; Double C2-Like Domains; Beta; Doc2-Beta; DOC2BL; Double C2-Like Domain-Containing Protein Beta; Double C2-Like Domains; Beta-Like;