NoGeneST™ Anti-HNRNPA1 Aptamer, aHNRNPA1 aptamer-1 sodium

Name: NoGeneST™ Anti-HNRNPA1 Aptamer, aHNRNPA1 aptamer-1 sodium
SKU: NRYF-0625-HZ15
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-HZ15]

Sodium-stabilized ssDNA aptamer that specifically recognizes the intracellular cancer-associated protein, hnRNP A1.

Target:: Heterogeneous nuclear ribonucleoprotein hnRNP A1

Type:: DNA

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Product Overview

Description

This is an engineered single-stranded DNA (ssDNA) aptamer developed to selectively bind with high specificity to heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1). Given that hnRNP A1 is frequently overexpressed within the nucleus of various cancer cells, this aptamer acts as a precise molecular probe for cancer diagnostics, imaging, and targeted cell identification.

Type

DNA

Relevant Diseases

Cancer

Properties

Size

1 mg; 5 mg; 10 mg

Appearance

Supplied as a lyophilized white to off-white solid.

Purity

>90%

Shipping

Room temperature

Storage

Powder Form: Stable for 3 years when stored at -20°C.
In Solvent: Stable for 6 months when aliquoted and stored at -80°C

Research Use Only

For Research Use Only

Target Details

Target

Heterogeneous nuclear ribonucleoprotein hnRNP A1

Alternative Names

hnRNP-A1; HNRPA1; UP 1 (ssDNA-binding protein UP1)

Gene ID

3178

Uniprot ID

P09651

Target Overview

Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a ubiquitous and abundant RNA-binding protein critical for nucleic acid metabolism. It plays a key role in many cellular processes, including the alternative splicing of pre-mRNAs, mRNA transport from the nucleus to the cytoplasm, and the regulation of translation. While essential for normal cell function, hnRNP A1 is very often overexpressed in a wide range of cancers. This overexpression is linked to tumorigenesis and cancer progression, making hnRNP A1 a significant cancer biomarker and a high-value target for diagnostic probes and novel therapeutic strategies.

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