NoGeneST™ Anti-α-Synuclein Aptamer

Name: NoGeneST™ Anti-α-Synuclein Aptamer
SKU: NRYF-0625-HZ90
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-HZ90]

Aptamer designed to specifically recognize Alpha-Synuclein, a key protein central to the pathology of Parkinson's disease and other synucleinopathies.

Target:: α-Synuclein

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Product Overview

Relevant Diseases

Parkinson's Disease

Properties

Size

5 nmol. 10 nmol. 50 nmol

Soluble In

PBS; buffer system with Serum; other

Purity

>90%

Shipping

Room temperature

Storage

Powder Form: Stable for 3 years when stored at -20°C.
In Solvent: Stable for 6 months when aliquoted and stored at -80°C

Research Use Only

For Research Use Only

Target Details

Target

α-Synuclein

Full Name

Alpha-Synuclein

Alternative Names

SNCA; NACP; PARK1

Gene ID

6622

Uniprot ID

P37840

Target Overview

Alpha-synuclein is a protein that is abundant in the human brain, where it is found primarily at the tips of neurons in specialized structures called presynaptic terminals. Although its exact function is not fully understood, it is thought to play a role in regulating the release of neurotransmitters. Alpha-synuclein is most notable for its central role in a group of neurodegenerative disorders known as "synucleinopathies." In these diseases, the protein misfolds and aggregates into insoluble fibrils that accumulate in neurons as Lewy bodies and Lewy neurites. These aggregates are the defining pathological hallmark of Parkinson's disease, dementia with Lewy bodies (DLB), and multiple system atrophy (MSA).

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