CD38 Activity Assay Kit, All

Description

Cluster of differentiation (CD38), also known as cyclic ADP ribose hydrolase, is a multifunctional enzyme that can catalyze the synthesis and hydrolysis of nicotinamide adenine dinucleotide (NAD) into nicotinamide and ADP-ribose (ADPR). In addition, CD38 uses NAD as a substrate to generate a second messenger, cyclic ADP-ribose (cADPR). Because of its role in NAD + metabolism, the study of CD38 and its functions is very important. CD38 is involved in regulating NAD + metabolism, aging and other diseases (including obesity, diabetes, heart disease, asthma, inflammation, etc.). In addition, CD38 is expressed in lymphoid, myeloid, red blood cells and platelets, with the highest expression. Plasma cell. Plasma cells highly express CD38, making CD38 an ideal target for targeted immunotherapy. Our CD38 activity assay kit can be used to detect its activity in biological samples. This kit utilizes the ability of active CD38 to catalyze the conversion of CD38 substrates into fluorescent products (Ex / Em = 300/410 nm). The assay kit provides a fast, simple and sensitive method to detect CD38 activity in a variety of sample types.
• Measurement of CD38 activity in various tissues/cells
• Mechanistic studies of various cancers
• Screening anti-cancer drugs

Species Reactivity

Wide Species

Relevant Diseases

Neurological Disorders

Detection Method

Fluorescence (Ex/Em = 300/410 nm)

Assay Type

ELISA kit

Components

• CD38 Assay Buffer
• CD38 Lysis Buffer
• CD38 Substrate
• CD38 Positive Control
• CD38 Standard

Shipping

Gel Pack

Storage

-20°C

Research Use Only

For research use only

Target

CD38

Official Name

CD38

Full Name

CD38 molecule

Alternative Names

Acute lymphoblastic leukemia cells antigen CD38;
ADP ribosyl cyclase 1;
ADP ribosyl cyclase;
ADP ribosyl cyclase/cyclic ADP-ribose hydrolase;
ADP-ribosyl cyclase 1;
ADPRC 1;
ADPRC1;
cADPr hydrolase 1;
CD 38

Gene ID

952(Human)

Uniprot ID

P28907(Human)