Creative Biolabs

Mouse Anti-BDNF Monoclonal Antibody (1E5C5), Unconjugated

[CAT#: NAB20101813CR]

Mouse Monoclonal (1E5C5) to BDNF

Host Species:
Mouse
Species Reactivity:
Human
Applications:
IF; WB; ELISA

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Description
BDNF (brain-derived neurotrophic factor) is a small secreted growth factor that is important for the development and plasticity of the central nervous system and vital for long-term memory. Selected polymorphisms of BDNF have been shown to increase susceptibility to memory impairment and selected eating and mental disorders.
Expression Host
Mammalian cells
Immunogen
BDNF fusion protein Ag11329
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2a
Clone Number
1E5C5
Applications
IF; WB; ELISA
Application Notes
IF : 1:20-1:200; WB : 1:500-1:1000
Relevant Diseases
Neurological Disorders
Research Areas
Neural Signal Transduction
Conjugation
Unconjugated
Form
Liquid
Formulation
PBS, 0.1% sodium azide and 50% glycerol pH 7.3.
Preservatives
Yes
Concentration
1000 μg/ml
Purification
Antigen affinity purification
Purity
>95%, as determined by SDS-PAGE
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at -20°C. Stable for one year after shipment.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
BDNF
Official Name
BDNF
Full Name
Brain-derived neurotrophic factor
Alternative Names
Abrineurin; BDNF
Gene ID
627(Human); 12064(Mouse); 24225(Rat)
Uniprot ID
P23560(Human); P21237(Mouse); P23363(Rat)
1. Hayashi, N., Himi, N., Nakamura-Maruyama, E., Okabe, N., Sakamoto, I., Hasegawa, T., & Miyamoto, O. (2019). Improvement of motor function induced by skeletal muscle contraction in spinal cord-injured rats. The Spine Journal, 19(6), 1094-1105. 2. Kwon, H. J., Jung, H. Y., Hahn, K. R., Kim, W., Kim, J. W., Yoo, D. Y.,... & Kim, D. W. (2018). Bacopa monnieri extract improves novel object recognition, cell proliferation, neuroblast differentiation, brain-derived neurotrophic factor, and phosphorylation of cAMP response element-binding protein in the dentate gyrus. Laboratory animal research, 34(4), 239-247. 3. Zhou, P. T., Wang, L. P., Qu, M. J., Shen, H., Zheng, H. R., Deng, L. D.,... & Tian, H. L. (2019). Dl-3-N-butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats. CNS Neuroscience & Therapeutics, 25(6), 748-758.
Neural Cell Lines
Kits
Neural Antibodies
Neural Proteins & Peptides
Biomaterials
For Research Use Only. Not For Clinical Use.
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