Mouse Anti-BDNF Monoclonal Antibody (CBP2737)

Product Overview

Description

BDNF (brain-derived neurotrophic factor) is a small secreted growth factor that is important for the development and plasticity of the central nervous system and vital for long-term memory. Selected polymorphisms of BDNF have been shown to increase susceptibility to memory impairment and selected eating and mental disorders.

Expression Host

Mammalian cells

Immunogen

BDNF fusion protein Ag11329

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a

Clone Number

CBP2737

Applications

IF; WB; ELISA

Application Notes

IF : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Neural Signal Transduction

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

BDNF

Official Name

BDNF

Full Name

Brain-derived neurotrophic factor

Alternative Names

Abrineurin; BDNF

Gene ID

627(Human); 12064(Mouse); 24225(Rat)

Uniprot ID

P23560(Human); P21237(Mouse); P23363(Rat)

References

1. Hayashi, N., Himi, N., Nakamura-Maruyama, E., Okabe, N., Sakamoto, I., Hasegawa, T., & Miyamoto, O. (2019). Improvement of motor function induced by skeletal muscle contraction in spinal cord-injured rats. The Spine Journal, 19(6), 1094-1105. 2. Kwon, H. J., Jung, H. Y., Hahn, K. R., Kim, W., Kim, J. W., Yoo, D. Y.,... & Kim, D. W. (2018). Bacopa monnieri extract improves novel object recognition, cell proliferation, neuroblast differentiation, brain-derived neurotrophic factor, and phosphorylation of cAMP response element-binding protein in the dentate gyrus. Laboratory animal research, 34(4), 239-247. 3. Zhou, P. T., Wang, L. P., Qu, M. J., Shen, H., Zheng, H. R., Deng, L. D.,... & Tian, H. L. (2019). Dl-3-N-butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats. CNS Neuroscience & Therapeutics, 25(6), 748-758.

Publications