Creative Biolabs

Mouse Anti-IL-1 Beta Monoclonal Antibody (1A7), Unconjugated

[CAT#: NAB2007FY889]

Mouse Monoclonal [1A7] to IL-1 Beta

Host Species:
Mouse
Species Reactivity:
Human
Applications:
WB

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Description
Mouse anti-interleukin-1 beta. The protein encoded by IL1B is a member of the interleukin-1 cytokine family. This cytokine is produced by activated macrophages in the form of original protein, which is proteolyzed by caspase 1 (CASP1/ICE) into its active form. This cytokine is an important mediator of inflammatory response and participates in a variety of cell activities, including cell proliferation, differentiation and apoptosis. It was found that this cytokine induces cyclooxygenase 2 (PTGS2/COX2) in the central nervous system (CNS) to contribute to inflammatory pain hypersensitivity. IL1B and 8 other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (provided by RefSeq, July 2008).
Immunogen
HEK293-derived full-length recombinant IL-1 beta.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
1A7
Applications
WB
Application Notes
WB: 1/1000
Relevant Diseases
Amyotrophic Lateral Sclerosis; Frontotemporal Dementia
Conjugation
Unconjugated
Form
Liquid
Formulation
PBS, 0.09% Sodium Azide, 1% Bovine Serum Albumin
<50% Glycerol
Preservatives
YES
Concentration
1 mg/ml
Purification
Protein G
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Il-1β
Official Name
IL1B
Full Name
Interleukin 1 beta
Alternative Names
IL1B; IL-1; IL1-BETA; IL1F2; interleukin 1 beta; IL1beta
Gene ID
16176(Human)
Uniprot ID
P10749(Human)
Neural Proteins & Peptides
Neural Antibodies
Neural Genes
For Research Use Only. Not For Clinical Use.
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