Mouse Anti-IL-6 Monoclonal Antibody (CBP3001)

Description

Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.

Expression Host

Mammalian cells

Immunogen

Human IL-6 protein HZ-1019

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP3001

Applications

Neut; ELISA

Research Areas

Metabolism

Conjugation

Unconjugated

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

IL-6

Official Name

IL6

Full Name

Interleukin 6 (interferon, beta 2)

Alternative Names

Interleukin BSF 2;
B cell differentiation factor;
B cell stimulatory factor 2;
B-cell stimulatory factor 2;
BSF 2;
BSF-2;
BSF2;
CDF;
CTL differentiation factor;
Cytotoxic T cell differentiation factor;

Gene ID

3569(Human)

Uniprot ID

P05231(Human)