NeuroMab™ Anti-PHF Tau Antibody, Clone AT180

Product Overview

Description

The monoclonal antibody specifically recognizing PHF-tau. The monoclonal antibody did also equally recognize the phosphorylated wild-type tau.

Species Reactivity

Human; Mouse

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1 κ

Clone Number

AT180

Applications

ELISA; WB; In Vitro

Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

> 95% (SDS-PAGE)

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only

Target

PHF Tau

Official Name

PHF Tau

Full Name

Paired helical filament-tau

Alternative Names

PHF-Tau; MAPT; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; microtubule associated protein tau; Tau proteins; tau-40

Product Pictures

ELISA

Figure 1 Detection of PHF-tau and normal tau using monoclonal antibody AT180.

ELISA

Figure 2 Phosphorylation of wild-type and mutant recombinant tau (expressed from clone human tau 24; Goedert and Jakes, 1990) and protein kinase activity in rat brain.

Immunoblots with anti-tau antiserum 134 and monoclonal antibodies AT8 and AT180. Lanes 1, tau 24; 2, tau 24 plus brain extract; 3, T231 A tau 24; 4, T231 A tau 24 plus brain extract, 5, 5235 A tau 24; 6, S235 A tau 24 plus brain extract.

Publications