
NeuroMab™ Anti-PRNP BBB Shuttle Antibody, Clone 15B3
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IP; WB; ELISA; Inhib; In Vitro
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Figure 1. Western blot of normal bovine brain homogenate and recombinant bovine PrP. mAb 6H4 and 34C9 recognize bovine PrP and rbPrP, whereas may 15B3 recognizes only rbPrP Recombinant rbPrP runs lower and more acutely than PrP from brain homogenate because it is not glycosylated.

Figure 2 Conformation-sensitive ELIFA of brain homogenates of BSE diseased and normal bovines under different denaturation states. Stained with monoclonal antibody 15B3. In its native state, mAB 15B3 only stains bovine PrPSc, but not PrPC.
