NeuroMab™ Anti-PRNP BBB Shuttle Antibody, Clone 15B3
- Host Species:
- Species Reactivity:
- IP; WB; ELISA; Inhib; In Vitro
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Research Use Only
Figure 1. Western blot of normal bovine brain homogenate and recombinant bovine PrP. mAb 6H4 and 34C9 recognize bovine PrP and rbPrP, whereas may 15B3 recognizes only rbPrP Recombinant rbPrP runs lower and more acutely than PrP from brain homogenate because it is not glycosylated.
Figure 2 Conformation-sensitive ELIFA of brain homogenates of BSE diseased and normal bovines under different denaturation states. Stained with monoclonal antibody 15B3. In its native state, mAB 15B3 only stains bovine PrPSc, but not PrPC.