NeuroMab™ Mouse Anti-CD68 Monoclonal Antibody (CBP1586)

Product Overview

Description

Mouse anti-human CD68 antibody recognizes human CD68 cell surface antigen, a ~110 kDa glycoprotein mainly expressed by macrophages and monocytes.

Immunogen

Subcellular fraction of human alveolar macrophages.

Species Reactivity

Human; Primate; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP1586

Applications

FC; IF; IHC-P; IP; WB

Relevant Diseases

Alzheimer's Disease

Research Areas

Growth and Development

Conjugation

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1372

Product Properties

Form

Liquid

Formulation

PBS
0.09% Sodium Azide

Concentration

1 mg/ml

Purification

Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at +4°C or at -20°C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend micr°Centrifugation before use

Target

CD68

Official Name

CD68

Full Name

CD68 Molecule

Alternative Names

CD68 Molecule; CD68 Antigen; Scavenger Receptor Class D, Member 1; Macrophage Antigen CD68; GP110; Macrosialin; SCARD1; LAMP4

Gene ID

968(Human); 12514(Mouse); 287435(Rat)

Uniprot ID

P34810(Human); P31996(Mouse)

References

1. Pulford, K.A. et al. (1989) KP1: a new monoclonal antibody that detects a monocyte/macrophage associated antigen in routinely processed tissue sections.
2. Xiao, J. et al. (2016) Effects of ketanserin on experimental colitis in mice and macrophage function.
3. Masaki, T. et al. (2004) Activation of the extracellular-signal regulated protein kinase pathway in human glomerulopathies.
4. Vroon, A. et al. (2007) Neuroinflammation in Parkinson's patients and MPTP-treated mice is not restricted to the nigrostriatal system: microgliosis and differential expression of interleukin-1 receptors in the olfactory bulb.
5. Schwarz, F. et al. (2016) Human-specific derived alleles of CD33 and other genes protect against postreproductive cognitive decline.

Publications