Product Overview

Immunogen

Recombinant human RUNX1 (amino acids 191-453) expressed in E. coli.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Rat

Isotype

IgG2a, κ

Clone Number

CBP2460

Applications

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

Batch Dependent

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

RUNX1

Official Name

RUNX1

Full Name

Runt Related Transcription Factor 1

Alternative Names

Runt Related Transcription Factor 1; Polyomavirus Enhancer-Binding Protein 2 Alpha B Subunit; SL3 AKV Core-Binding Factor Alpha B Subunit; SL3-3 Enhancer Factor 1 Alpha B Subunit; Runt-Related Transcription Factor 1; Acute Myeloid Leukemia 1 Protein; Oncogene AML-1; PEBP2-Alpha B; PEA2-Alpha B; CBFA2; AML1; Core-Binding Factor; Runt Domain; Alpha Subunit 2;

Gene ID

861(Human)

Uniprot ID

Q01196(Human)

References

1. Goyama S, et al. 2013. J. Clin. Invest. 123:3876.
2. Wang J, et al. 2013. PLoS One. 18:e74255.
3. Taniuchi I, et al. 2012. EMBO J. 31:4098.
4. Neel BG, et al. 2012. Genes Dev. 26:1520.
5. Della Gatta G, et al. 2012. Nat. Med. 18:436.
6. Hoi CS, et al. 2010. Mol. Cell Biol. 30:2518.

Publications