Product
Mouse Anti-PTPRC Monoclonal Antibody (CBP2656)
[CAT#: NAB20101730CR]
Mouse Monoclonal (4E9B2) to PTPRC
- Host Species:
- Mouse
- Species Reactivity:
- Human; Porcine; Mouse
- Applications:
- FC; IF; IHC; WB; ELISA
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
CD45 is an enzyme required for T-cell activation through the antigen receptor consisting of two intracellular phosphatase domains, a transmembrane domain and an extracellular domain. Upon T-cell activation, CD45 recruits and dephosphorylates SKAP1 via an interaction through the first PTPase domain, which is the only domain to possess intrinsic kinase activity. However, both domains are required for appropriate phosphatase and T-cell antigen receptor activity.
Expression Host
Mammalian cells
Immunogen
CD45 fusion protein Ag13712
Species Reactivity
Human; Porcine; Mouse
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2a
Clone Number
CBP2656
Applications
FC; IF; IHC; WB; ELISA
Application Notes
IF : 1:20-1:200; IHC : 1:20-1:200; WB : 1:500-1:1000
Research Areas
Metabolism
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, 0.1% sodium azide and 50% glycerol pH 7.3.
Preservatives
Yes
Concentration
1667 μg/ml
Purification
Antigen affinity purification
Purity
>95%, as determined by SDS-PAGE
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at -20°C. Stable for one year after shipment.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Li, Q., Zhai, Y., Man, X., Zhang, S., & An, X. (2020). Inhibition of DNA Methyltransferase by RG108 Promotes Pluripotency-Related Character of Porcine Bone Marrow Mesenchymal Stem Cells. Cellular Reprogramming, 22(2), 82-89. 2. Matsunari, H., Watanabe, M., Hasegawa, K., Uchikura, A., Nakano, K., Umeyama, K.,... & Nishinakamura, R. (2020). Compensation of Disabled Organogeneses in Genetically Modified Pig Fetuses by Blastocyst Complementation. Stem cell reports, 14(1), 21-33.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
