Mouse Anti-CD68 Monoclonal Antibody (CBP2721)

Product Overview

Description

CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages.

Expression Host

Mammalian cells

Immunogen

CD68 fusion protein Ag22815

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2721

Applications

IHC; ELISA

Application Notes

IHC : 1:20-1:200

Research Areas

Metabolism

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1007 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

CD68

Official Name

CD68

Full Name

CD68 molecule

Alternative Names

CD68;
CD68 antigen;
CD68 molecule;

Gene ID

968(Human); 12514(Mouse); 287435(Rat)

Uniprot ID

P34810(Human); P31996(Mouse)

References

1. Gou, Y., Li, X., Li, P., Zhang, H., Xu, T., Wang, H.,... & Zhang, Z. (2019). Estrogen receptor β upregulates CCL2 via NF-κB signaling in endometriotic stromal cells and recruits macrophages to promote the pathogenesis of endometriosis. Human Reproduction, 34(4), 646-658. 2. Yang, H., Li, J., Yang, C., Liu, H., & Cao, Y. (2019). Multi-walled carbon nanotubes promoted lipid accumulation in human aortic smooth muscle cells. Toxicology and applied pharmacology, 374, 11-19.

Publications