Mouse Anti-NEFM Monoclonal Antibody (CBP2761)

Product Overview

Description

NEFM belongs to the intermediate filament family. Neurofilaments are the 10 nm intermediate filaments found specifically in neurons. They are a major component of the cell's cytoskeleton, and provide support for normal axonal radial growth. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.

Expression Host

Mammalian cells

Immunogen

NF-M fusion protein Ag22709

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2761

Applications

IHC; WB; ELISA

Application Notes

IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Neural Cell

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

NEFM

Official Name

NEFM

Full Name

Neurofilament, medium polypeptide

Alternative Names

68 kDa neurofilament protein;
AI847934;
CMT1F;
CMT2CC;
CMT2E;
FLJ53642;
KIAA0845;
light molecular weight neurofilament protein;
Micro glutamic acid-rich protein;
mKIAA0845;
Nef3;
NEFH;

Gene ID

4744(Human)

Uniprot ID

P07196(Human)

References

1. Sun, D., Yang, L., Cao, H., Shen, Z. Y., & Song, H. L. (2020). Study of the protective effect on damaged intestinal epithelial cells of rat multilineage-differentiating stress-enduring (Muse) cells. Cell biology international, 44(2), 549-559. 2. Pacheco, N. L., Heaven, M. R., Holt, L. M., Crossman, D. K., Boggio, K. J., Shaffer, S. A.,... & Olsen, M. L. (2017). RNA sequencing and proteomics approaches reveal novel deficits in the cortex of Mecp2-deficient mice, a model for Rett syndrome. Molecular autism, 8(1), 56.

Publications