Mouse Anti-HIP1 Monoclonal Antibody (CBP2919)

Product Overview

Description

HIP1 (huntingtin interacting protein-1) is a endocytic protein that plays a role in clathrin-mediated endocytosis and trafficking. HIP1 can interact with huntingtin (HTT) protein whose mutations cause Huntington's disease (HD), thus gets involved in neurodegeneration. By stabilizing receptor tyrosine kinases following ligand-induced endocytosis, HIP1 may act to promote cell survival. HIP1 is overexpressed in a variety of human cancers and may be a potential predictor for cancer progression and prognosis.

Expression Host

Mammalian cells

Immunogen

HIP1 fusion protein Ag17982

Species Reactivity

Human; Mouse; Porcine

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2919

Applications

IHC; WB; ELISA

Application Notes

IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Metabolism

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

HIP1

Official Name

HIP1

Full Name

Huntingtin interacting protein 1

Alternative Names

HIP I;
HIP-1;
HIP-I;
hip1;
HIP1/PDGFRB fusion gene;

Gene ID

3092(Human); 215114(Mouse); 192154(Rat)

Uniprot ID

O00291(Human); Q8VD75(Mouse)

References

1. Icli, B., Wu, W., Ozdemir, D., Li, H., Haemmig, S., Liu, X.,... & Lee, N. (2019). MicroRNA-135a-3p regulates angiogenesis and tissue repair by targeting p38 signaling in endothelial cells. The FASEB Journal, 33(4), 5599-5614.

Publications