Anti-PME-1 Monoclonal Antibody (CBP3684)
[CAT#: NAB201216LS]
Anti-PME-1 Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human; Rat
- Applications:
- WB; IHC
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Protein phosphatase methylesterase-1 (PME-1) is an enzyme that catalyzes the demethylation and inactivation of protein phosphatase (PP2A). PP2A is a heterotrimeric serine/threonine phosphatase that regulates proteins of oncogenic signaling pathways such as Raf, MEK and Akt. PP2A is associated with growth inhibition and cell cycle arrest.
Immunogen
HIS-tagged, full-length mouse PME1 protein
Species Reactivity
Human; Rat
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
CBP3684
Applications
WB; IHC
Application Notes
WB (0.5-10 µg/mL); IHC (10 µg/mL
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.
Concentration
1.0 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
PME-1
Official Name
PME-1
Full Name
PME-1
Alternative Names
PME-1
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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