Mouse Anti-Rat CD86 Monoclonal Antibody (CBP3935)
[CAT#: NAB2012753LS]
Anti-CD86 Monoclonal Antibody, Conjugated
- Host Species:
- Mouse
- Species Reactivity:
- Rat
- Applications:
- FC
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. D86 has been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Immunogen
LPS-activated CBA/Ca mouse splenic B cells
Species Reactivity
Rat
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2a, κ
Clone Number
CBP3935
Applications
FC
Application Notes
FCM (5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.
Concentration
1.0 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
CD86
Official Name
CD86
Full Name
CD86 molecule
Alternative Names
CD86; CD86 molecule
Gene ID
942(Human)
References
1. Hathcock K, et al. 1996. Adv. Immunol. 62:131.
2. June C, et al. 1994. Immunol. Today 15:321.
2. June C, et al. 1994. Immunol. Today 15:321.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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