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Creative Biolabs

Mouse Anti-Rat CCL11 Monoclonal Antibody (CBP4022)

[CAT#: NAB20121040LS]

Anti-CCL11 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Rat
Applications:
ELISA

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Product Overview

Description

CCL11 selectively recruits eosinophils by binding to the chemokine receptor CCR3 during allergies. In response to several pro-inflammatory cytokines (such as IL-4, IL-13, TNF-α and IFN-α) produced by mast cells and Th2 lymphocytes, the production of CCL11 is up-regulated. It has been reported that CCL11 stimulates the release of eosinophils from the bone marrow, leading to an increase in circulating eosinophils.

Immunogen

Recombinant Mouse CCL11, (amino acids (His24-Pro97, Accession# NM_011330), were expressed in E. coli.

Species Reactivity

Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP4022

Applications

ELISA

Application Notes

ELISA (0.5 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CCL11

Official Name

CCL11

Full Name

C-C motif chemokine 11

Alternative Names

SCYA11; C-C motif chemokine 11; Eosinophil chemotactic protein; Eotaxin; Small-inducible cytokine A11

Gene ID

6356(Human);20292(Mouse)

Uniprot ID

P51671(Human);P48298(Mouse)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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