Rat Anti-Human CCL11 Monoclonal Antibody (CBP4021)
[CAT#: NAB20121039LS]
Anti-CCL11 Monoclonal Antibody
- Host Species:
- Rat
- Species Reactivity:
- Human
- Applications:
- WB
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
CCL11 selectively recruits eosinophils by binding to the chemokine receptor CCR3 during allergies. In response to several pro-inflammatory cytokines (such as IL-4, IL-13, TNF-α and IFN-α) produced by mast cells and Th2 lymphocytes, the production of CCL11 is up-regulated. It has been reported that CCL11 stimulates the release of eosinophils from the bone marrow, leading to an increase in circulating eosinophils.
Immunogen
Human CCL11 recombinant protein (Gly24-Pro97) expressed in E. coli.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Rat
Isotype
IgG2a
Clone Number
CBP4021
Applications
WB
Application Notes
WB (0.5-2.0 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.
Concentration
1.0 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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