Anti-AMIGO-1 Monoclonal Antibody (CBP4027)

Product Overview

Description

Amphoterin-induced protein 1 (AMIGO-1) is a transmembrane protein containing six LRR domains and one Ig domain and is highly expressed in the mammalian nervous system. Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. AMIGO-1 may have a role in regeneration as well as neural plasticity in the adult nervous system.

Immunogen

This monoclonal antibody was raised against a fusion protein corresponding to amino acids 395-493 (cytoplasmic C-terminus) of human AMIGO-1.

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b

Clone Number

CBP4027

Applications

WB; IHC-P

Application Notes

WB (1.0-10.0 µg/mL); IHC-P (5.0-10.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

AMIGO-1

Official Name

AMIGO1

Full Name

Adhesion Molecule With Ig Like Domain 1

Alternative Names

Adhesion Molecule With Ig Like Domain 1; Alivin-2; AMIGO-1; AMIGO; ALI2; Amphoterin-Induced Gene And Open Reading Frame; Amphoterin-Induced Gene And ORF; Amphoterin-Induced Protein 1; KIAA1163;