5-HT1A shRNA Plasmid Expression Vector Set

Name: 5-HT1A shRNA Plasmid Expression Vector Set
SKU: NRYF-0925-XY362
Rating: 5 (1 reviews)

[CAT#: NRYF-0925-XY362]

Target:: 5-HT1A

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Product Overview

Description

An effective kit for the specific knockdown of the 5-HT1A serotonin receptor. The set provides three distinct shRNA plasmid vectors targeting the 5-HT1A receptor mRNA, along with a scrambled shRNA plasmid as a negative control. It allows researchers to investigate the precise role of this key receptor in regulating mood and anxiety, and to validate it as a therapeutic target.

Properties

Size

5-50 μg

Shipping

Ambient

Storage

4°C

Research Use Only

Target Details

Target

5-HT1A

Full Name

Brain-Derived Neurotrophic Factor

Gene ID

627

Uniprot ID

P23560

Target Overview

Brain-Derived Neurotrophic Factor (BDNF) is a key member of the neurotrophin family of growth factors, which are proteins that support the growth, survival, and differentiation of neurons. BDNF is highly active in the brain and peripheral nervous system, where it is essential for regulating synaptic plasticity, the molecular process that underlies learning and memory. It also plays a crucial role in promoting neuron repair and regeneration. Dysregulation of BDNF levels or signaling has been implicated in the pathophysiology of many neurological and psychiatric disorders, including depression, Alzheimer's disease, and schizophrenia.

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