NoGeneST™ Anti-5-HT1A Aptamer, a5-HT1A aptamer

Name: NoGeneST™ Anti-5-HT1A Aptamer, a5-HT1A aptamer
SKU: NRYF-0625-HZ120
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-HZ120]

Aptamer designed to specifically recognize the 5-HT1A receptor, a key serotonin receptor and a major target for antidepressant and anxiolytic drugs.

Target:: 5-HT1A

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Product Overview

Relevant Diseases

Depression

Properties

Size

5 nmol. 10 nmol. 50 nmol

Soluble In

PBS; buffer system with Serum; other

Purity

>90%

Shipping

Room temperature

Storage

Powder Form: Stable for 3 years when stored at -20°C.
In Solvent: Stable for 6 months when aliquoted and stored at -80°C

Research Use Only

For Research Use Only

Target Details

Target

5-HT1A

Full Name

5-Hydroxytryptamine Receptor 1A

Gene ID

3350

Uniprot ID

P08908

Target Overview

The 5-HT1A receptor is a G protein-coupled receptor (GPCR) and one of the principal receptors for the neurotransmitter serotonin (5-hydroxytryptamine). It is widely distributed throughout the central nervous system, where it plays a critical dual role. As a postsynaptic receptor, it modulates neuronal excitability, while as a presynaptic autoreceptor on serotonin neurons, it provides inhibitory feedback to reduce serotonin synthesis and release. Due to its fundamental involvement in the regulation of mood and emotion, the 5-HT1A receptor is a major therapeutic target for anxiolytic (anti-anxiety) and antidepressant medications.

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