AAV2/2 Plus-mCaMKIIa-eNpHR 3.0-EGFP-WPRE-pA

Name: AAV2/2 Plus-mCaMKIIa-eNpHR 3.0-EGFP-WPRE-pA
SKU: NTA-2012-ZP82
Rating: 5 (1 reviews)

[CAT#: NTA-2012-ZP82]

Tracer Type:: Optogenetics

Applications:: Optogenetics

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Product Overview

Description

NpHR, a light-driven chloride ion pump, belongs to Halorhodopsin. The common version is NpHR3.0, which adds the endoplasmic reticulum forward transport signal and the Golgi transport signal to the cell membrane on the basis of NpHR, which improves its expression on the cell membrane and is the most commonly used photoinhibition tool. NpHR is usually driven by yellow light around 570nm and can be used simultaneously with hChR2 (H134R).

The mCaMKIIa promoter, cloned from the promoter region of mouse calmodulin-dependent protein kinase IIa, is 1.3 kb in length, and is specifically expressed in excitatory neuronal cells.