DNMT1 ELISA Kit, Human

Description

Methylated CpG residues. Preferential methylation of hemimethylated DNA. It associates with DNA replication sites in the S phase and maintains the methylation pattern in the newly synthesized strand, which is essential for epigenetics. It associates with chromatin in the G2 and M stages to maintain DNA methylation, regardless of replication. It is responsible for maintaining the methylation pattern established in development. It is also necessary to maintain the transcriptional repression of genes in undifferentiated embryonic stem cells (ESC). Our DNMT1 ELISA kit is a sandwich ELISA assay for the quantitative measurement of human DNMT1 in serum, plasma and cell culture supernatant. The density of the color is proportional to the amount of DNMT1 captured from the sample.
This ELISA kit is used for quantitative measurement of DNMT1 in serum, plasma, tissue homogenates, culture supernatants and other biological fluids.

Species Reactivity

Human

Relevant Diseases

Neurological Disorders

Sensitivity

< 0.094 ng/ml

Detection Method

Absorbance (450 nm)

Assay Type

ELISA kit

Detection Range

0.156 -10 ng/ml

Components

• Microplate: 96 wells
• Lyophilized Standard
• Sample / Standard dilution buffer
• Biotin- detection antibody (Concentrated)
• Antibody dilution buffer
• HRP-Streptavidin Conjugate (SABC)
• SABC dilution buffer
• TMB substrate
• Stop Solution
• Wash buffer (25X)
• Plate sealers

Shipping

Gel Pack

Storage

4°C

Research Use Only

For research use only

Target

DNMT1

Official Name

DNMT1

Full Name

DNA (cytosine-5-)-methyltransferase 1

Alternative Names

ADCADN;
AIM;
CXXC finger protein 9;
CXXC-type zinc finger protein 9;
CXXC9;
DNA (cytosine 5) methyltransferase 1;
DNA (cytosine-5)-methyltransferase 1;
DNA methyltransferase 1;
DNA methyltransferase HsaI;
DNA methyltransferase M.HsaI.

Gene ID

1786(Human); 13433(Mouse); 84350(Rat)

Uniprot ID

P26358(Human); P13864(Mouse); Q9Z330(Rat)